Location: Home >> Effect and Mechanism Study of Bu Zhong Yi Qi Tang in Treating Cancer-related Fatigue in Patients with Digestive System Tumors of Qi and Blood Deficiency Type
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Objective: To investigate the mechanism of action and clinical efficacy of Bu Zhong Yi Qi Tang in the treatment of cancer-related fatigue in patients with digestive tract tumors of Qi and Blood deficiency type. Methods: Ninety patients with cancer-related fatigue due to Qi and Blood deficiency type digestive tract tumors, admitted to our hospital from June 2022 to June 2023, were selected as the study subjects. They were randomly divided into the control group (n=45) and the experimental group (n=45). The control group received conventional Western medicine treatment, while the experimental group received Bu Zhong Yi Qi Tang in addition to conventional treatment. The Chinese medicine syndrome score, fatigue level (PFS score), and incidence of adverse reactions were compared between the two groups before and after treatment. Results: Before treatment, there was no statistically significant difference in the Chinese medicine syndrome score and PFS score between the two groups (P>0.05). After treatment, the Chinese medicine syndrome score and PFS score of both groups decreased compared to before treatment (P<0.05), and the experimental group had a lower Chinese medicine syndrome score and PFS score than the control group (P<0.05). The incidence of adverse reactions in the experimental group was 4.44%, higher than the control group's 8.89%, but the difference between the two groups was not statistically significant (P>0.05). Conclusion: Bu Zhong Yi Qi Tang is effective in improving clinical symptoms and reducing fatigue levels in patients with cancer-related fatigue due to Qi and Blood deficiency type digestive tract tumors, and it is relatively safe.
 Zhang, X., & Zhang, Y. (2022). Efficacy of Bushen Yiqi Decoction combined with syndrome differentiation scraping therapy in the treatment of cancer-related fatigue in digestive tract tumors and its effects on T lymphocyte subgroups. Journal of Modern Traditional Chinese Medicine, 31(8), 1100-1104.
 Tian, L., & Hu, Y. (2017). Key points interpretation of the 2017 NCCN clinical practice guidelines for cancer-related fatigue. Shanghai Nursing, 17(1), 9-13.
 National Administration of Traditional Chinese Medicine. (1994). Diagnostic criteria and efficacy standards for traditional Chinese medicine diseases and syndromes. Nanjing: Nanjing University Press.
 Chen, S., Dong, M., & Wu, Y. (2020). Effects of Bushen Yiqi Decoction combined with ear acupressure on immune function and serum cortisol in cancer-related fatigue patients with digestive tract tumors. Shaanxi Journal of Traditional Chinese Medicine, 41(9), 1241-1244.
 Pellat, A., Coriat, R. (2020). Well Differentiated Grade 3 Neuroendocrine Tumors of the Digestive Tract: A Narrative Review. J. Clin. Med., 2020, 9, 1677. https://doi.org/10.3390/jcm9061677.
 Pobłocki, J., Jasińska, A., Syrenicz, A., Andrysiak-Mamos, E., Szczuko, M. (2020). The Neuroendocrine Neoplasms of the Digestive Tract: Diagnosis, Treatment and Nutrition. Nutrients, 2020, 12, 1437. https://doi.org/10.3390/nu12051437.
Liyan Zhang, Jinhui Zhang, Hongxiang Liu, Yongchen Zhao, Huanhuan Miao. Effect and Mechanism Study of Bu Zhong Yi Qi Tang in Treating Cancer-related Fatigue in Patients with Digestive System Tumors of Qi and Blood Deficiency Type. International Journal of Medicine Frontiers, 2023, 6(2), 48-51.